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The Mechanisms of PD-L1 Regulation in Non-Small-Cell Lung Cancer (NSCLC): Which Are the Involved Players?

SIMPLE SUMMARY: Immunotherapy against PD-1/PD-L1 dramatically improved outcomes in non-small cell lung cancer patients. These treatments are more effective the higher the expression of PD-L1 on tumor cells, reported as tumor proportion score. However, PD-L1 expression can be highly variable, dependi...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Lamberti, Giuseppe, Sisi, Monia, Andrini, Elisa, Palladini, Arianna, Giunchi, Francesca, Lollini, Pier-Luigi, Ardizzoni, Andrea, Gelsomino, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692442/
https://ncbi.nlm.nih.gov/pubmed/33114576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113129
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