HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection

HIV-1 genetic diversity can be used to infer time since infection (TSI) and infection recency. We adapted this approach for HCV and identified genomic regions with informative diversity. We included 72 HCV/HIV-1 coinfected participants of the Swiss HIV Cohort Study, for whom reliable estimates of in...

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Vydáno v:Viruses
Hlavní autoři: Carlisle, Louisa A., Turk, Teja, Metzner, Karin J., Mbunkah, Herbert A., Shah, Cyril, Böni, Jürg, Huber, Michael, Braun, Dominique L., Fehr, Jan, Salazar-Vizcaya, Luisa, Rauch, Andri, Yerly, Sabine, Nguyen, Aude, Cavassini, Matthias, Stoeckle, Marcel, Vernazza, Pietro, Bernasconi, Enos, Günthard, Huldrych F., Kouyos, Roger D.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692400/
https://ncbi.nlm.nih.gov/pubmed/33142675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12111241
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