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Formation of an RNA Quadruplex-Duplex Hybrid in Living Cells between mRNA of the Epidermal Growth Factor Receptor (EGFR) and a G-Rich Antisense Oligoribonucleotide

Antisense DNA oligonucleotides, short interfering RNAs (siRNAs), and CRISPR/Cas9 genetic tools are the most useful therapeutic nucleic acids regulating gene expression based on the antisense specificity towards messenger RNA. Here, we present an effective novel strategy for inhibiting translation ba...

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Pubblicato in:Cells
Autori principali: Gudanis, Dorota, Kaniowski, Damian, Kulik, Katarzyna, Baranowski, Daniel, Gdaniec, Zofia, Nawrot, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692301/
https://ncbi.nlm.nih.gov/pubmed/33138194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112375
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