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Anakinra Reduces Epileptogenesis, Provides Neuroprotection, and Attenuates Behavioral Impairments in Rats in the Lithium–Pilocarpine Model of Epilepsy

Temporal lobe epilepsy is a widespread chronic disorder that manifests as spontaneous seizures and is often characterized by refractoriness to drug treatment. Temporal lobe epilepsy can be caused by a primary brain injury; therefore, the prevention of epileptogenesis after a primary event is conside...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Dyomina, Alexandra V., Zubareva, Olga E., Smolensky, Ilya V., Vasilev, Dmitry S., Zakharova, Maria V., Kovalenko, Anna A., Schwarz, Alexander P., Ischenko, Alexander M., Zaitsev, Aleksey V.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692198/
https://ncbi.nlm.nih.gov/pubmed/33113868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13110340
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