Dysbindin deficiency Alters Cardiac BLOC-1 Complex and Myozap Levels in Mice

Dysbindin, a schizophrenia susceptibility marker and an essential constituent of BLOC-1 (biogenesis of lysosome-related organelles complex-1), has recently been associated with cardiomyocyte hypertrophy through the activation of Myozap-RhoA-mediated SRF signaling. We employed sandy mice (Dtnbp1_KO),...

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Publicado no:Cells
Main Authors: Borlepawar, Ankush, Schmiedel, Nesrin, Eden, Matthias, Christen, Lynn, Rosskopf, Alexandra, Frank, Derk, Lüllmann-Rauch, Renate, Frey, Norbert, Rangrez, Ashraf Yusuf
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692170/
https://ncbi.nlm.nih.gov/pubmed/33142804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112390
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