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Physioxia Stimulates Extracellular Matrix Deposition and Increases Mechanical Properties of Human Chondrocyte-Derived Tissue-Engineered Cartilage

Cartilage tissue has been recalcitrant to tissue engineering approaches. In this study, human chondrocytes were formed into self-assembled cartilage sheets, cultured in physiologic (5%) and atmospheric (20%) oxygen conditions and underwent biochemical, histological and biomechanical analysis at 1- a...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Dennis, James E., Whitney, George Adam, Rai, Jyoti, Fernandes, Russell J., Kean, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691651/
https://ncbi.nlm.nih.gov/pubmed/33282851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.590743
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