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(68)Ga, (44)Sc and (177)Lu-labeled AAZTA(5)-PSMA-617: synthesis, radiolabeling, stability and cell binding compared to DOTA-PSMA-617 analogues

BACKGROUND: The AAZTA chelator and in particular its bifunctional derivative AAZTA(5) was recently investigated to demonstrate unique capabilities to complex diagnostic and therapeutic trivalent radiometals under mild conditions. This study presents a comparison of (68)Ga, (44)Sc and (177)Lu-labeled...

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Detalhes bibliográficos
Publicado no:EJNMMI Radiopharm Chem
Main Authors: Sinnes, Jean-Philippe, Bauder-Wüst, Ulrike, Schäfer, Martin, Moon, Euy Sung, Kopka, Klaus, Rösch, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691401/
https://ncbi.nlm.nih.gov/pubmed/33242189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-020-00107-8
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