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Fibrinolysis-resistant carbonylated fibrin detected in thrombi attached to the vascular wall of abdominal aortic aneurysms

In this study, we investigated how carbonylation of fibrinogen by acrolein modified its indispensable function to enhance fibrinolysis after being converted to fibrin and contributed to generating a fibrinolysis-resistant fibrin clot. Acrolein-treated fibrinogen was subjected to tissue plasminogen a...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Suzuki, Yuko, Tanaka, Hiroki, Horinouchi, Takahiro, Sano, Hideto, Honkura, Naoki, Unno, Naoki, Miwa, Soichi, Urano, Tetsumei
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691368/
https://ncbi.nlm.nih.gov/pubmed/33244022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77582-1
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