Fibrinolysis-resistant carbonylated fibrin detected in thrombi attached to the vascular wall of abdominal aortic aneurysms

In this study, we investigated how carbonylation of fibrinogen by acrolein modified its indispensable function to enhance fibrinolysis after being converted to fibrin and contributed to generating a fibrinolysis-resistant fibrin clot. Acrolein-treated fibrinogen was subjected to tissue plasminogen a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Suzuki, Yuko, Tanaka, Hiroki, Horinouchi, Takahiro, Sano, Hideto, Honkura, Naoki, Unno, Naoki, Miwa, Soichi, Urano, Tetsumei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691368/
https://ncbi.nlm.nih.gov/pubmed/33244022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77582-1
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