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Targeting P53 as a Future Strategy to Overcome Gemcitabine Resistance in Biliary Tract Cancers

Gemcitabine-based chemotherapy is the current standard treatment for biliary tract cancers (BTCs) and resistance to gemcitabine remains the clinical challenge. TP53 mutation has been shown to be associated with poor clinicopathologic characteristics and survival in patients with BTCs, indicating tha...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Wu, Chiao-En, Pan, Yi-Ru, Yeh, Chun-Nan, Lunec, John
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690712/
https://ncbi.nlm.nih.gov/pubmed/33113997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10111474
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