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The PTEN Conundrum: How to Target PTEN-Deficient Prostate Cancer
Loss of the tumor suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN), which negatively regulates the PI3K–AKT–mTOR pathway, is strongly linked to advanced prostate cancer progression and poor clinical outcome. Accordingly, several therapeutic approaches are currently being e...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7690430/ https://ncbi.nlm.nih.gov/pubmed/33105713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112342 |
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