Phase 0 and window of opportunity clinical trial design in neuro-oncology: a RANO review

Glioblastoma is a devastating disease with poor prognosis. Few effective chemotherapeutics are currently available, and much effort has been expended to identify new drugs capable of slowing tumor progression. The phase 0 trial design was developed to facilitate early identification of promising age...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Vogelbaum, Michael A, Krivosheya, Daria, Borghei-Razavi, Hamid, Sanai, Nader, Weller, Michael, Wick, Wolfgang, Soffietti, Riccardo, Reardon, David A, Aghi, Manish K, Galanis, Evanthia, Wen, Patrick Y, van den Bent, Martin, Chang, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690357/
https://ncbi.nlm.nih.gov/pubmed/32598442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa149
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