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The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection

The novel coronavirus SARS-CoV-2 enters into the human body mainly through the ACE2 + TMPRSS2+ nasal epithelial cells. The initial host response to this pathogen occurs in a peculiar immune microenvironment that, starting from the Nasopharynx-Associated Lymphoid Tissue (NALT) system, is the product...

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Bibliographic Details
Published in:Mucosal Immunol
Main Authors: Gallo, Oreste, Locatello, Luca Giovanni, Mazzoni, Alessio, Novelli, Luca, Annunziato, Francesco
Format: Artigo
Language:Inglês
Published: © Society for Mucosal Immunology. Published by Elsevier Inc. 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690066/
https://ncbi.nlm.nih.gov/pubmed/33244161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-00359-2
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