Computational Approaches to Identify Molecules Binding to Mycobacterium tuberculosis KasA

[Image: see text] Tuberculosis is caused by Mycobacterium tuberculosis (Mtb) and is a deadly disease resulting in the deaths of approximately 1.5 million people with 10 million infections reported in 2018. Recently, a key condensation step in the synthesis of mycolic acids was shown to require β-ket...

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Publié dans:ACS Omega
Auteurs principaux: Puhl, Ana C., Lane, Thomas R., Vignaux, Patricia A., Zorn, Kimberley M., Capodagli, Glenn C., Neiditch, Matthew B., Freundlich, Joel S., Ekins, Sean
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689923/
https://ncbi.nlm.nih.gov/pubmed/33251429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04271
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