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Fluorescent multiplexing of 3D spheroids: Analysis of biomarkers using automated immunohistochemistry staining platform and multispectral imaging

In preclinical cancer studies, three‐dimensional (3D) cell spheroids and aggregates are preferred over monolayer cell cultures due to their architectural and functional similarity to solid tumors. We performed a proof‐of‐concept study to generate physiologically relevant and predictive preclinical m...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Bhaumik, Srabani, Boyer, Jean, Banerjee, Chaitali, Clark, Samantha, Sebastiao, Noemi, Vela, Elizabeth, Towne, Penny
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689845/
https://ncbi.nlm.nih.gov/pubmed/32692912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.29827
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