Recombinant Human BMP6 Applied Within Autologous Blood Coagulum Accelerates Bone Healing: Randomized Controlled Trial in High Tibial Osteotomy Patients

Bone morphogenetic proteins (BMPs) are potent osteogenic proteins that induce new bone formation in vivo. However, their effect on bone healing in the trabecular bone surfaces remains challenging. We evaluated the safety and efficacy of recombinant human BMP6 (rhBMP6) applied within an autologous bl...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Chiari, Catharina, Grgurevic, Lovorka, Bordukalo‐Niksic, Tatjana, Oppermann, Hermann, Valentinitsch, Alexander, Nemecek, Elena, Staats, Kevin, Schreiner, Markus, Trost, Carmen, Kolb, Alexander, Kainberger, Franz, Pehar, Sanja, Milosevic, Milan, Martinovic, Snjezana, Peric, Mihaela, Sampath, T Kuber, Vukicevic, Slobodan, Windhager, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689741/
https://ncbi.nlm.nih.gov/pubmed/32543706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4107
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