Relative contributions of family history and a polygenic risk score on COPD and related outcomes: COPDGene and ECLIPSE studies

INTRODUCTION: Family history is a risk factor for chronic obstructive pulmonary disease (COPD). We previously developed a COPD risk score from genome-wide genetic markers (Polygenic Risk Score, PRS). Whether the PRS and family history provide complementary or redundant information for predicting COP...

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Dades bibliogràfiques
Publicat a:BMJ Open Respir Res
Autors principals: Moll, Matthew, Lutz, Sharon M., Ghosh, Auyon J., Sakornsakolpat, Phuwanat, Hersh, Craig P., Beaty, Terri H., Dudbridge, Frank, Tobin, Martin D., Mittleman, Murray A., Silverman, Edwin K., Hobbs, Brian D., Cho, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2020
Matèries:
Chronic Obstructive Pulmonary Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689586/
https://ncbi.nlm.nih.gov/pubmed/33239407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjresp-2020-000755
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