A Key GWAS-Identified Genetic Variant Contributes to Hyperlipidemia by Upregulating miR-320a

It has been unclear whether the elevated levels of the circulating miR-320a in patients with coronary artery disease is due to environmental influence or genetic basis. By recombinant adeno-associated virus (rAAV)-mediated loss- and gain-of-function studies in the mouse liver, we revealed that eleva...

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Publicado no:iScience
Main Authors: Yin, Zhongwei, Zhao, Yanru, Du, Hengzhi, Nie, Xiang, Li, Huaping, Fan, Jiahui, He, Mengying, Dai, Beibei, Zhang, Xudong, Yuan, Shuai, Wen, Zheng, Chen, Chen, Wang, Dao Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689551/
https://ncbi.nlm.nih.gov/pubmed/33294796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101788
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