Large genome-wide association study identifies three novel risk variants for restless legs syndrome

Restless legs syndrome (RLS) is a common neurological sensorimotor disorder often described as an unpleasant sensation associated with an urge to move the legs. Here we report findings from a meta-analysis of genome-wide association studies of RLS including 480,982 Caucasians (cases = 10,257) and a...

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Pubblicato in:Commun Biol
Autori principali: Didriksen, Maria, Nawaz, Muhammad Sulaman, Dowsett, Joseph, Bell, Steven, Erikstrup, Christian, Pedersen, Ole B., Sørensen, Erik, Jennum, Poul J., Burgdorf, Kristoffer S., Burchell, Brendan, Butterworth, Adam S., Soranzo, Nicole, Rye, David B., Trotti, Lynn Marie, Saini, Prabhjyot, Stefansdottir, Lilja, Magnusson, Sigurdur H., Thorleifsson, Gudmar, Sigmundsson, Thordur, Sigurdsson, Albert P., Van Den Hurk, Katja, Quee, Franke, Tanck, Michael W. T., Ouwehand, Willem H., Roberts, David J., Earley, Eric J., Busch, Michael P., Mast, Alan E., Page, Grier P., Danesh, John, Di Angelantonio, Emanuele, Stefansson, Hreinn, Ullum, Henrik, Stefansson, Kari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689502/
https://ncbi.nlm.nih.gov/pubmed/33239738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01430-1
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