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Lipopolysaccharide directly inhibits bicarbonate absorption by the renal outer medullary collecting duct

Acidosis is associated with E. coli induced pyelonephritis but whether bacterial cell wall constituents inhibit HCO(3) transport in the outer medullary collecting duct from the inner stripe (OMCDi) is not known. We examined the effect of lipopolysaccharide (LPS), on HCO(3) absorption in isolated per...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Tsuruoka, Shuichi, Purkerson, Jeffrey M., Schwartz, George J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689453/
https://ncbi.nlm.nih.gov/pubmed/33239624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77363-w
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