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Lipopolysaccharide directly inhibits bicarbonate absorption by the renal outer medullary collecting duct

Acidosis is associated with E. coli induced pyelonephritis but whether bacterial cell wall constituents inhibit HCO(3) transport in the outer medullary collecting duct from the inner stripe (OMCDi) is not known. We examined the effect of lipopolysaccharide (LPS), on HCO(3) absorption in isolated per...

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Pubblicato in:Sci Rep
Autori principali: Tsuruoka, Shuichi, Purkerson, Jeffrey M., Schwartz, George J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689453/
https://ncbi.nlm.nih.gov/pubmed/33239624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77363-w
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