Immunogenicity of a single-dose compared with a two-dose primary series followed by a booster dose of ten-valent or 13-valent pneumococcal conjugate vaccine in South African children: an open-label, randomised, non-inferiority trial

BACKGROUND: Routine childhood immunisation with pneumococcal conjugate vaccine (PCV) has changed the epidemiology of pneumococcal disease across age groups, providing an opportunity to reconsider PCV dosing schedules. We aimed to evaluate the post-booster dose immunogenicity of ten-valent (PCV10) an...

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Pubblicato in:Lancet Infect Dis
Autori principali: Madhi, Shabir A, Mutsaerts, Eleonora AML, Izu, Alane, Boyce, Welekazi, Bhikha, Sutika, Ikulinda, Benit T, Jose, Lisa, Koen, Anthonet, Nana, Amit J, Moultrie, Andrew, Roalfe, Lucy, Hunt, Adam, Goldblatt, David, Cutland, Clare L, Dorfman, Jeffrey R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science ;, The Lancet Pub. Group 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689288/
https://ncbi.nlm.nih.gov/pubmed/32857992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(20)30289-9
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