Hydrophobic Mycobacterial Antigens Elicit Polyfunctional T Cells in Mycobacterium bovis Immunized Cattle: Association With Protection Against Challenge?

Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a chronic disease of cattle with a detrimental impact on food quality and production. Research on bTB vaccines has predominantly been focused on proteinaceous antigens. However, mycobacteria have a thick and intricate lipid outer layer and...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Benedictus, Lindert, Steinbach, Sabine, Holder, Thomas, Bakker, Douwe, Vrettou, Christina, Morrison, W. Ivan, Vordermeier, Martin, Connelley, Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688591/
https://ncbi.nlm.nih.gov/pubmed/33281817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.588180
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