Impact of granulocyte colony‐stimulating factor on FOLFIRINOX‐induced neutropenia prevention: A population pharmacokinetic/pharmacodynamic approach

AIMS: Granulocyte colony‐stimulating factor (G‐CSF) is frequently prescribed to prevent chemotherapy‐induced neutropenia, but the administration schedule remains empirical in case of bimonthly chemotherapy such as FOLFIRINOX regimen. This pharmacokinetic/pharmacodynamic (PK/PD) study was performed t...

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Библиографические подробности
Опубликовано в: :Br J Clin Pharmacol
Главные авторы: Macaire, Pauline, Paris, Justine, Vincent, Julie, Ghiringhelli, François, Bengrine‐Lefevre, Leïla, Schmitt, Antonin
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688541/
https://ncbi.nlm.nih.gov/pubmed/32386071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14356
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