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TRAIL of Hope Meeting Resistance in Cancer

TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with death receptors TRAILR1/death receptor 4 (DR4) and TRAILR2/DR5 in a wide range of cancers while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAI...

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Bibliographic Details
Published in:Trends Cancer
Main Authors: Deng, David, Shah, Khalid
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688478/
https://ncbi.nlm.nih.gov/pubmed/32718904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.06.006
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