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Immunophenotype based on inflammatory cells, PD-1/PD-L1 signalling pathway and M2 macrophages predicts survival in gastric cancer

BACKGROUND: Immune response against cancer has prognostic impact but its role in gastric cancer is poorly known. The aim of the study was to assess the prognostic significance of immune cell score (CD3+, CD8+), tumour immune escape (PD-L1, PD-1) and immune tolerance (Clever-1). METHODS: After exclus...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Junttila, Anna, Helminen, Olli, Väyrynen, Juha P., Ahtiainen, Maarit, Kenessey, Istvan, Jalkanen, Sirpa, Mecklin, Jukka-Pekka, Kellokumpu, Ilmo, Kuopio, Teijo, Böhm, Jan, Mrena, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687887/
https://ncbi.nlm.nih.gov/pubmed/32943749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01053-7
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