CircSOD2 induced epigenetic alteration drives hepatocellular carcinoma progression through activating JAK2/STAT3 signaling pathway

BACKGROUND: Emerging evidence suggests that circular RNAs play critical roles in disease development especially in cancers. Previous genome-wide RNA-seq studies found that a circular RNA derived from SOD2 gene was highly upregulated in hepatocellular carcinoma (HCC), however, the role of circSOD2 in...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Zhao, Zhongwei, Song, Jingjing, Tang, Bufu, Fang, Shiji, Zhang, Dengke, Zheng, Liyun, Wu, Fazong, Gao, Yang, Chen, Chunmiao, Hu, Xianghua, Weng, Qiaoyou, Yang, Yang, Tu, Jianfei, Ji, Jiansong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687771/
https://ncbi.nlm.nih.gov/pubmed/33234142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01769-7
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