CompLement C5 Antibodies for decreasing brain injury after aneurysmal Subarachnoid Haemorrhage (CLASH): study protocol for a randomised controlled phase II clinical trial

BACKGROUND: The inflammatory response after aneurysmal subarachnoid haemorrhage (aSAH) has been associated with early brain injury, delayed cerebral ischaemia, poor functional outcome, and case fatality. In experimental SAH studies, complement C5 antibodies administered shortly after SAH reduced bra...

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Detalles Bibliográficos
Publicado en:Trials
Autores principales: Koopman, Inez, Rinkel, Gabriel J. E., Vergouwen, Mervyn D. I.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687754/
https://ncbi.nlm.nih.gov/pubmed/33239044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04838-6
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