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CompLement C5 Antibodies for decreasing brain injury after aneurysmal Subarachnoid Haemorrhage (CLASH): study protocol for a randomised controlled phase II clinical trial

BACKGROUND: The inflammatory response after aneurysmal subarachnoid haemorrhage (aSAH) has been associated with early brain injury, delayed cerebral ischaemia, poor functional outcome, and case fatality. In experimental SAH studies, complement C5 antibodies administered shortly after SAH reduced bra...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Koopman, Inez, Rinkel, Gabriel J. E., Vergouwen, Mervyn D. I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687754/
https://ncbi.nlm.nih.gov/pubmed/33239044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04838-6
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