TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41

Transcription factor EB (TFEB) activates lysosomal biogenesis genes in response to environmental cues. Given implications of impaired TFEB signaling and lysosomal dysfunction in metabolic, neurological, and infectious diseases, we aim to systematically identify TFEB-directed circuits by examining tr...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Carey, Kimberly L., Paulus, Geraldine L.C., Wang, Lingfei, Balce, Dale R., Luo, Jessica W., Bergman, Phil, Ferder, Ianina C., Kong, Lingjia, Renaud, Nicole, Singh, Shantanu, Kost-Alimova, Maria, Nyfeler, Beat, Lassen, Kara G., Virgin, Herbert W., Xavier, Ramnik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686957/
https://ncbi.nlm.nih.gov/pubmed/33176151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108371
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