Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients

BK polyomavirus (BKPyV) infection is a major complication of hematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT). Treatment options are limited, poorly effective, and have significant toxicities. Cellular therapy using T cells directed against BKPyV is an emerging therapy, and...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Nelson, Adam S., Heyenbruch, Daria, Rubinstein, Jeremy D., Sabulski, Anthony, Jodele, Sonata, Thomas, Shawn, Lutzko, Carolyn, Zhu, Xiang, Leemhuis, Thomas, Cancelas, Jose A., Keller, Michael, Bollard, Catherine M., Hanley, Patrick J., Davies, Stella M., Grimley, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686882/
https://ncbi.nlm.nih.gov/pubmed/33216887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003073
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