Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal-weight polycystic ovary syndrome (PCOS) women during adipogenesis: evidence of cellular programming

BACKGROUND: Normal-weight polycystic ovary syndrome (PCOS) women exhibit adipose resistance in vivo accompanied by enhanced subcutaneous (SC) abdominal adipose stem cell (ASC) development to adipocytes with accelerated lipid accumulation per cell in vitro. The present study examines chromatin access...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Epigenetics
Principais autores: Leung, Karen L., Sanchita, Smriti, Pham, Catherine T., Davis, Brett A., Okhovat, Mariam, Ding, Xiangming, Dumesic, Phillip, Grogan, Tristan R., Williams, Kevin J., Morselli, Marco, Ma, Feiyang, Carbone, Lucia, Li, Xinmin, Pellegrini, Matteo, Dumesic, Daniel A., Chazenbalk, Gregorio D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686698/
https://ncbi.nlm.nih.gov/pubmed/33228780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00970-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados