Distinct Age-Related Epigenetic Signatures in CD4 and CD8 T Cells

Healthy immune aging is in part determined by how well the sizes of naïve T cell compartments are being maintained with advancing age. Throughout adult life, replenishment largely derives from homeostatic proliferation of existing naïve and memory T cell populations. However, while the subpopulation...

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Udgivet i:Front Immunol
Main Authors: Hu, Bin, Jadhav, Rohit R., Gustafson, Claire E., Le Saux, Sabine, Ye, Zhongde, Li, Xuanying, Tian, Lu, Weyand, Cornelia M., Goronzy, Jörg J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686576/
https://ncbi.nlm.nih.gov/pubmed/33262764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585168
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