HIF-1α Directly Controls WNT7A Expression During Myogenesis

Herein we unveil that Hypoxia-inducible factor-1α (HIF-1α) directly regulates WNT7A expression during myogenesis. In fact, chromatin immunoprecipitation (ChiP) and site-directed mutagenesis experiments revealed two distinct hypoxia response elements (HREs) that are specific HIF-1α binding sites on t...

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Udgivet i:Front Cell Dev Biol
Main Authors: Cirillo, Federica, Resmini, Giulia, Angelino, Elia, Ferrara, Michele, Tarantino, Adriana, Piccoli, Marco, Rota, Paola, Ghiroldi, Andrea, Monasky, Michelle M., Ciconte, Giuseppe, Pappone, Carlo, Graziani, Andrea, Anastasia, Luigi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686515/
https://ncbi.nlm.nih.gov/pubmed/33262987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.593508
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