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Immortalisation of primary human alveolar epithelial lung cells using a non-viral vector to study respiratory bioreactivity in vitro

To overcome the scarcity of primary human alveolar epithelial cells for lung research, and the limitations of current cell lines to recapitulate the phenotype, functional and molecular characteristics of the healthy human alveolar epithelium, we have developed a new method to immortalise primary hum...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Katsumiti, Alberto, Ruenraroengsak, Pakatip, Cajaraville, Miren P., Thorley, Andrew J., Tetley, Teresa D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686381/
https://ncbi.nlm.nih.gov/pubmed/33235275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77191-y
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