Modulation of granulosa cell function via CRISPR-Cas fuelled editing of BMPR-IB gene in goats (Capra hircus)

BMPs are multifunctional growth factors implicated in regulating the ovarian function as key intra-ovarian factors. Biological effects of BMPs are mediated through binding with membrane bound receptors like BMPR-IB and initiating downstream Smad signaling pathway. FecB mutation, regarded as a loss o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kumar, Sai, Punetha, Meeti, Jose, Bosco, Bharati, Jaya, Khanna, Shivani, Sonwane, Arvind, Green, Jonathan A., Whitworth, Kristin, Sarkar, Mihir
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686318/
https://ncbi.nlm.nih.gov/pubmed/33235250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77596-9
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