Cyr61 synthesis is induced by interleukin-6 and promotes migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

BACKGROUND: Interleukin-6 (IL-6) is involved in fibroblast-like synoviocyte (FLS) activation and promotes pannus formation and bone and cartilage destruction in rheumatoid arthritis (RA). Cysteine-rich 61 (Cyr61) protein regulates cell proliferation, migration, and differentiation. The aim of this s...

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Bibliographic Details
Published in:Arthritis Res Ther
Main Authors: Choi, Changmin, Jeong, Wooseong, Ghang, Byeongzu, Park, Yonggeun, Hyun, Changlim, Cho, Moonjae, Kim, Jinseok
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685583/
https://ncbi.nlm.nih.gov/pubmed/33228785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02369-8
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