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LncRNA MIR4435-2HG mediates cisplatin resistance in HCT116 cells by regulating Nrf2 and HO-1

PURPOSE: Cisplatin resistance is still a serious problem in the clinic. However, the underlying mechanism remains unknown. In our study, we investigated cisplatin resistance by using the cisplatin-resistant cell line HCT116R. METHODS: The HCT116 cell line, a colon cancer cell line, was purchased. Ce...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Luo, Ping, Wu, Shugui, Ji, Kaibao, Yuan, Xia, Li, Hongmi, Chen, Jinping, Tian, Yunfei, Qiu, Yang, Zhong, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685444/
https://ncbi.nlm.nih.gov/pubmed/33232319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223035
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