Identification of Caffeic Acid Phenethyl Ester (CAPE) as a Potent Neurodifferentiating Natural Compound That Improves Cognitive and Physiological Functions in Animal Models of Neurodegenerative Diseases

Cell-based screening of bioactive compounds has served as an important gateway in drug discovery. In the present report, using human neuroblastoma cells and enrolling an extensive three-step screening of 57 phytochemicals, we have identified caffeic acid phenethyl ester (CAPE) as a potent neurodiffe...

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Bibliographic Details
Published in:Front Aging Neurosci
Main Authors: Konar, Arpita, Kalra, Rajkumar Singh, Chaudhary, Anupama, Nayak, Aashika, Guruprasad, Kanive P., Satyamoorthy, Kapaettu, Ishida, Yoshiyuki, Terao, Keiji, Kaul, Sunil C., Wadhwa, Renu
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685006/
https://ncbi.nlm.nih.gov/pubmed/33244299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.561925
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