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BDCA1(+) cDC2s, BDCA2(+) pDCs and BDCA3(+) cDC1s reveal distinct pathophysiologic features and impact on clinical outcomes in melanoma patients

OBJECTIVES: Dendritic cells play a pivotal but still enigmatic role in the control of tumor development. Composed of specialised subsets (cDC1s, cDC2s, pDCs), DCs are critical in triggering and shaping antitumor immune responses. Yet, tumors exploit plasticity of DCs to subvert their functions and e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Immunology
Hauptverfasser: Sosa Cuevas, Eleonora, Ouaguia, Laurissa, Mouret, Stephane, Charles, Julie, De Fraipont, Florence, Manches, Olivier, Valladeau‐Guilemond, Jenny, Bendriss‐Vermare, Nathalie, Chaperot, Laurence, Aspord, Caroline
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7684973/
https://ncbi.nlm.nih.gov/pubmed/33282290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1190
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