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Mixed logistic regression in genome-wide association studies

BACKGROUND: Mixed linear models (MLM) have been widely used to account for population structure in case-control genome-wide association studies, the status being analyzed as a quantitative phenotype. Chen et al. proved in 2016 that this method is inappropriate in some situations and proposed GMMAT,...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Milet, Jacqueline, Courtin, David, Garcia, André, Perdry, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7684894/
https://ncbi.nlm.nih.gov/pubmed/33228527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03862-2
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