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Mesenchymal stem cells negatively regulate CD4(+) T cell activation in patients with primary Sjögren syndrome through the miRNA-125b and miRNA-155 TCR pathway
Treatment with mesenchymal stem cells (MSCs) has been revealed to suppress CD4(+) T cells and autoimmunity in both mouse models and patients with primary Sjögren syndrome (pSS); however, the underlying mechanism remains unclear. MicroRNAs (miRNAs or miRs) mediate CD4(+) T cell activation, but the me...
Gespeichert in:
| Veröffentlicht in: | Mol Med Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7684863/ https://ncbi.nlm.nih.gov/pubmed/33179091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11681 |
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