Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells

Osteoclasts (OCs) and much less dendritic cells (DCs) induce significant expansion and functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially increase the expansion and activation of CD8+ T cells by targeting CD4+ T cells. When autologous OCs were used to expand...

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Vydáno v:Sci Rep
Hlavní autoři: Kaur, Kawaljit, Ko, Meng-Wei, Ohanian, Nick, Cook, Jessica, Jewett, Anahid
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683603/
https://ncbi.nlm.nih.gov/pubmed/33230147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76702-1
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