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(89)Zr-pro-MMP-9 F(ab′)(2) detects colitis induced intestinal and kidney fibrosis

Intestinal fibrosis is a common complication of inflammatory bowel disease but remains difficult to detect. Matrix metalloproteases (MMPs) have key roles in fibrosis and are therefore potential targets for fibrosis detection. We determined whether immunoPET of F(ab′)(2) antibody fragments targeting...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Dmochowska, Nicole, Tieu, William, Keller, Marianne D., Hollis, Courtney A., Campaniello, Melissa A., Mavrangelos, Chris, Takhar, Prab, Hughes, Patrick A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683569/
https://ncbi.nlm.nih.gov/pubmed/33230169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77390-7
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