Proglucagon-Derived Peptides Expression and Secretion in Rat Insulinoma INS-1 Cells

Rat insulinoma INS-1 cells are widely used to study insulin secretory mechanisms. Studies have shown that a population of INS-1 cells are bi-hormonal, co-expressing insulin, and proglucagon proteins. They coined this population as immature cells since they co-secrete proglucagon-derived peptides fro...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Acosta-Montalvo, Ana, Saponaro, Chiara, Kerr-Conte, Julie, Prehn, Jochen H. M., Pattou, François, Bonner, Caroline
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683504/
https://ncbi.nlm.nih.gov/pubmed/33240888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.590763
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