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Blockade of Orexin Receptors in the Posterior Paraventricular Nucleus of the Thalamus Prevents Stress-Induced Reinstatement of Reward-Seeking Behavior in Rats With a History of Ethanol Dependence

Neural systems involved in processing natural rewards and drugs of abuse overlap and exposure to drugs of abuse induce neuroadaptations that can cause compulsive-like behavior. For example, the recruitment of the orexin (Orx) system by drugs of abuse has been proposed to induce neuroadaptations that...

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Veröffentlicht in:Front Integr Neurosci
Hauptverfasser: Matzeu, Alessandra, Martin-Fardon, Rémi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683390/
https://ncbi.nlm.nih.gov/pubmed/33240054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnint.2020.599710
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