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Diffusion MRI Detects Early Brain Microstructure Abnormalities in 2-month-old 3xTg-AD Mice

The 3xTg-AD mouse is one of the most studied animal modes of AD, and develops both amyloid-β deposits and neurofibrillary tangles in a temporal and spatial pattern that is similar to human AD pathology. Additionally, abnormal myelination patterns with changes in oligodendrocyte and myelin marker exp...

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Detalhes bibliográficos
Publicado no:NMR Biomed
Main Authors: Falangola, Maria Fatima, Nie, Xingju, Ward, Ralph, McKinnon, Emilie T., Dhiman, Siddhartha, Nietert, Paul J., Helpern, Joseph A., Jensen, Jens H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683375/
https://ncbi.nlm.nih.gov/pubmed/32557874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.4346
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