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In vivo targeting of miR‐223 in experimental eosinophilic oesophagitis

OBJECTIVES: Eosinophilic oesophagitis (EoE) is characterised by oesophageal inflammation, fibrosis and dysfunction. Micro (mi)‐RNAs interfere with pro‐inflammatory and pro‐fibrotic transcriptional programs, and miR‐223 was upregulated in oesophageal mucosal biopsy specimens from EoE patients. The th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Immunology
Hauptverfasser: Collison, Adam M, Sokulsky, Leon A, Nightingale, Scott, Percival, Elizabeth, LeFevre, Anna, Meredith, Joseph, Krauss, Sybille, Foster, Paul S, Mattes, Joerg
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683276/
https://ncbi.nlm.nih.gov/pubmed/33282292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1210
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