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In vivo targeting of miR‐223 in experimental eosinophilic oesophagitis

OBJECTIVES: Eosinophilic oesophagitis (EoE) is characterised by oesophageal inflammation, fibrosis and dysfunction. Micro (mi)‐RNAs interfere with pro‐inflammatory and pro‐fibrotic transcriptional programs, and miR‐223 was upregulated in oesophageal mucosal biopsy specimens from EoE patients. The th...

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Bibliographic Details
Published in:Clin Transl Immunology
Main Authors: Collison, Adam M, Sokulsky, Leon A, Nightingale, Scott, Percival, Elizabeth, LeFevre, Anna, Meredith, Joseph, Krauss, Sybille, Foster, Paul S, Mattes, Joerg
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683276/
https://ncbi.nlm.nih.gov/pubmed/33282292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1210
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