Astrocytic TSPO Upregulation Appears Before Microglial TSPO in Alzheimer’s Disease

BACKGROUND: In vivo PET/SPECT imaging of neuroinflammation is primarily based on the estimation of the 18 kDa-translocator-protein (TSPO). However, TSPO is expressed by different cell types which complicates the interpretation. OBJECTIVE: The present study evaluates the cellular origin of TSPO alter...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Tournier, Benjamin B., Tsartsalis, Stergios, Ceyzériat, Kelly, Fraser, Ben H., Grégoire, Marie-Claude, Kövari, Enikö, Millet, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683091/
https://ncbi.nlm.nih.gov/pubmed/32804124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200136
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