High Cholesterol Diet Exacerbates Blood-Brain Barrier Disruption in LDLr–/– Mice: Impact on Cognitive Function

BACKGROUND: Evidence has revealed an association between familial hypercholesterolemia and cognitive impairment. In this regard, a connection between cognitive deficits and hippocampal blood-brain barrier (BBB) breakdown was found in low-density lipoprotein receptor knockout mice (LDLr–/–), a mouse...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: de Oliveira, Jade, Engel, Daiane F., de Paula, Gabriela C., dos Santos, Danúbia B., Lopes, Jadna B., Farina, Marcelo, Moreira, Eduardo L.G., de Bem, Andreza F.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683087/
https://ncbi.nlm.nih.gov/pubmed/32925052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200541
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