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Genetic variability in sodium-glucose cotransporter 2 influences glycemic control and risk for diabetic retinopathy in type 2 diabetes patients

BACKGROUND: Gluconeogenesis and renal glucose excretion in kidneys both play an important role in glucose homeostasis. Sodium-glucose cotransporter (SGLT2), coded by the SLC5A2 gene is responsible for reabsorption up to 99% of the filtered glucose in proximal tubules. SLC5A2 genetic polymorphisms we...

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Vydáno v:J Med Biochem
Hlavní autoři: Klen, Jasna, Goričar, Katja, Dolžan, Vita
Médium: Artigo
Jazyk:Inglês
Vydáno: Society of Medical Biochemists of Serbia, Belgrade 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682783/
https://ncbi.nlm.nih.gov/pubmed/33269015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/jomb-2019-0040
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