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Production of the cytokine VEGF-A by infiltrating CD4(+) T and myeloid cells disrupts the corneal nerve landscape and promotes herpes stromal keratitis
Herpes simplex virus type 1 (HSV-1) infected corneas can develop a blinding immunoinflammatory condition called herpes stromal keratitis (HSK), which involves the loss of corneal sensitivity due to retraction of sensory nerves and subsequent hyperinnervation with sympathetic nerves. Increased concen...
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| Publicado no: | Immunity |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7682749/ https://ncbi.nlm.nih.gov/pubmed/33207210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.10.013 |
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