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The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration

Tauopathies are a class of neurodegenerative diseases associated with pathological tau. Despite many advances in our understanding of these diseases, the direct mechanism through which tau contributes to neurodegeneration remains poorly understood. Previously, our laboratory implicated the histone d...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Engstrom, Amanda K., Walker, Alicia C., Moudgal, Rohitha A., Myrick, Dexter A., Kyle, Stephanie M., Bai, Yu, Rowley, M. Jordan, Katz, David J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682552/
https://ncbi.nlm.nih.gov/pubmed/33139560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013552117
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